Pubblicazioni scientifiche

103 pubblicazioni, una domanda ricorrente.

Le pubblicazioni scientifiche del prof. Gianesini spaziano dalle scienze di base (fisica applicata al sistema vascolare) alla diagnostica vascolare avanzata, dallo sviluppo di tecniche e strategie mini-invasive per la cura veno-linfatica allo sviluppo di linee guida nazionali ed internazionali. In comune, il voler mettere al centro il paziente con la sua specificità.

Presentazione delle raccomandazioni multi-specialistiche in Senato.
Presentazione delle raccomandazioni multi-specialistiche in Senato.

Documenti di riferimento

  1. Gianesini S, Danese M, Pagano M, et al. Multi-specialty recommendations for the appropriate and affordable lower limb vein-lymphatic disorders management. Int Angiol. 2026 Feb;45(1):1-64. PubMed ↗
  2. Gianesini S, Chi YW, Agüero C, et al. Fake-news-free evidence-based communication for proper vein-lymphatic disease management. Int Angiol. 2023 Apr;42(2):89-189. PubMed ↗
  3. Gianesini S, Obi A, Onida S, et al. Global guidelines trends and controversies in lower limb venous and lymphatic disease. Phlebology. 2019 Sep;34(1 Suppl):4-66. PubMed ↗

Elenco completo

  1. 001Gianesini S, Danese M, Pagano M, et al. Multi-specialty recommendations for the appropriate and affordable lower limb vein-lymphatic disorders management. Int Angiol. 2026 Feb;45(1):1-64.
  2. 002Lazarov A, Goranova E, Gianesini S. Reliability assessment of artificial intelligence autonomously generated diagnostics & treatment plans. Acta Phlebologica 2025, in press.
  3. 003Diaz JA, Gianesini S, Khalil RA. Glycocalyx disruption, endothelial dysfunction and vascular remodeling as underlying mechanisms and treatment targets of chronic venous disease. Int Angiol. 2024 Dec;43(6):563-590.
  4. 004Ors Yildirim N, Yildirim AK, Demeli Ertus M, Dastan AO, Pehlivanoglu B, Chi YW, Gianesini S, Doganci S, Yildirim V. Sulodexide inhibits arterial contraction via the endothelium-dependent nitric oxide pathway. J Clin Med. 2024;13(8):2332.
  5. 005Salerno M, Bissacco D, Chi YW, Narayanan S, Addis A, Dellavia C, Canciani E, Righini PC, Nano G, Gianesini S. Empty vein ablation (EVA) technique: an in-vivo animal model to assess the effects of sclerosing agent concentration and wall contact time on intima and media tunicae structure. Int Angiol. 2024 Mar 21.
  6. 006Kavallieros K, Pope T, Tan M, Kaur H, Gianesini S, Lazarashvili Z, Jaworucka-Kaczorowska A, Narayanan S, Gwozdz AM, Davies AH. Identification of outcomes in clinical studies for pelvic venous disorders. J Vasc Surg Venous Lymphat Disord. 2024 Mar 5:101865.
  7. 007Tan M, Moreno HB, Bechter-Hugl B, Gianesini S, Connor D, Parsi K, Davies AH. Sclerotherapy: indications and safety volumes. Phlebology. 2024 Mar;39(2):135-138.
  8. 008Tan M, Bauza Moreno H, Thomis S, Canata V, Gianesini S, Parsi K, Davies AH. Truncal ablation: techniques. Phlebology. 2024 Mar;39(2):132-134.
  9. 009Tan M, Urbanek T, Rabe E, Gianesini S, Parsi K, Davies AH; UIP. Compression therapy in the management of varicose veins. Phlebology. 2023 Dec 15:2683555231222679.
  10. 010Ulloa JH, Lurie F, Santiago FR, Gianesini S, Reina L, Wang J, Jindal R, Taha W, Bokuchava M, Mansilha A. Systematic literature review and expert meeting report on health-related quality of life in chronic venous disease. Int Angiol. 2023 Dec;42(6):465-476.
  11. 011Gianesini S, De Luca L, Feodor T, Taha W, Bozkurt K, Lurie F. Cardiovascular insights for the appropriate management of chronic venous disease: a narrative review of implications for the use of venoactive drugs. Adv Ther. 2023 Sep 28.
  12. 012Gianesini S, Vagnoni E, Cavicchi C, Chi YW, Pagani A, Tessari M, Zamboni P, Menegatti E. Randomized controlled trial on occupational graduated compression clinical and cost-effectiveness. Int Angiol. 2023 Aug;42(4):344-351.
  13. 013Salerno M, Bissacco D, Chi YW, Narayanan S, Addis A, Dellavia C, Canciani E, Gard M, Gianesini S. Empty vein ablation innovative technique for chronic venous disease treatment: proof of concept and ex-vivo analysis. Int Angiol. 2023 Jun 28.
  14. 014Wong M, Parsi K, Myers K, De Maeseneer M, Caprini J, Cavezzi A, Connor DE, Davies AH, Gianesini S, et al. Sclerotherapy of lower limb veins: indications, contraindications and treatment strategies to prevent complications — a consensus document of the International Union of Phlebology 2023. Phlebology. 2023 May;38(4):205-258.
  15. 015Lobastov K, Urbanek T, Stepanov E, Lal BK, Marangoni J, Krauss ES, Cronin M, Dengler N, Segal A, Welch H, Gianesini S, Chen X, Caprini J. The thresholds of Caprini score associated with increased risk of venous thromboembolism across different specialties: a systematic review. Ann Surg. 2023 Mar 13.
  16. 016Gianesini S, Raffetto J, et al. Human lymphatic glycocalyx. Scientific Reports (Nature) 2023.
  17. 017Doganci S, Ince ME, Demeli M, Yildirim NO, Pehlivanoglu B, Yildirim AK, Gianesini S, Chi YW, Yildirim V. Sulodexide develops contraction in human saphenous vein via endothelium dependent nitric oxide pathway. J Clin Med 2023, in press.
  18. 018Fonseca MM, Mocelin FJ, Grill MH, Gianesini S, Miyake K, Argenta R, Pereira AH. Nd:YAG laser combined with injection sclerotherapy in the treatment of reticular veins and telangiectasias (CLaCS method): a triple-blind randomized clinical trial. Phlebology. 2023 Jan 19:2683555231153533.
  19. 019Menegatti E, Mandini S, Pagani A, Mandini B, Zerbini V, Piva T, Fabbri M, Fogli M, Mazzoni G, Zamboni P, Gianesini S. The effect of active stretching training in patients with chronic venous insufficiency monitored by raster-stereography. Sensors 2022, 8509.
  20. 020Menegatti E, Proto A, Paternò G, Gadda G, Gianesini S, Raisi A, Pagani A, Piva T, Zerbini V, Mazzoni G, Grazzi G, Taibi A, Zamboni P, Mandini S. The effect of submaximal exercise on jugular venous pulse assessed by a wearable cervical plethysmography system. Diagnostics 2022.
  21. 021Venturini E, Menegatti E, Gianesini S, Masiero S. Water-based exercise for upper and lower limb lymphoedema treatment. J Vasc Surg Venous Lymphat Disord 2022.
  22. 022Santiago FR, Ulloa J, Regnier C, Peudon T, Braund E, Fradet-Aubignat C, Gianesini S. The impact of lower limb chronic venous disease on quality of life: patient and physician perspectives. J Comp Eff Res (Epub ahead of print).
  23. 023Mansilha A, Gianesini S, Ulloa JH, Lobastov K, Wang J, Freitag A, Schaible KR, Martin M, Yaltirik P, Nicolaides AN. Pharmacological treatment for chronic venous disease: an umbrella review of systematic reviews. Int Angiol. 2022 Apr 4.
  24. 024Sousa J, Gianesini S, Mansilha A. Integrated anatomic and hemodynamic classification for primary superficial venous disease: results from an expert survey. Int Angiol. 2022 Mar 2.
  25. 025Butova X, Shayakhmetov S, Fedin M, Zolotukhin I, Gianesini S. Artificial intelligence for lower limb vein care improvement: available data and future directions. J Pers Med 2021, in press.
  26. 026Menegatti E, Mandini S, Chi YW, Mazzoni G, Pagani A, Malagoni AM, Tessari M, Costa AL, Avruscio G, Zamboni P, Gianesini S. Physical fitness changes induced by thermal aquatic standardized exercise in chronic venous disease patients. Phlebology. 2021 Oct 11:2683555211051962.
  27. 027Gianesini S, Bottini O, Menegatti E, Doganci S, Chi YW. Periuterine venous plexus thrombosis. Turk J Vasc Surg 2021, in press.
  28. 028Gianesini S, Bottini O, Menegatti E, Doganci S, Chi YW. Graduated compression venous plexus thrombosis. Turk J Vasc Surg 2021, in press.
  29. 029Gianesini S. Thrombosis & pelvic venous disorders. WIN Vasc Insights 2021;1:6-12.
  30. 030Menegatti E, Gianesini S, et al. Randomized controlled trial on dryland and thermal aquatic standardized exercise protocol for chronic venous disease (DATA study). J Vasc Surg Venous Lymphat Disord. 2021 Jan 9.
  31. 031Gianesini S. Segmental saphenous ablation for chronic venous disease treatment. Phlebology. 2021 Feb;36(1):63-69.
  32. 032Menegatti E, Gianesini S, et al. The effects of thermal water physical exercise in patients with lower limb chronic venous insufficiency monitored by bioimpedance analysis. Diagnostics (Basel). 2020 Oct 31;10(11):889.
  33. 033Miyake RK, Gianesini S, et al. State of the art on cryo-laser cryo-sclerotherapy in lower limb venous aesthetic treatment. J Vasc Surg Venous Lymphat Disord. 2020 Sep;8(5):893-895.
  34. 034Gianesini S, et al. Volume control of the lower limb with graduated compression during different muscle pump activation conditions and the relation to limb circumference variation. J Vasc Surg Venous Lymphat Disord. 2020 Sep;8(5):814-820.
  35. 035Gianesini S, et al. Case-control evaluation of the impact of below 20 mmHg elastic compression stockings on lower limb volume serial variations in standardized flights. Phlebology. 2020 Apr;35(3):199-206.
  36. 036Mander A, Gianesini S, et al. Upper limb secondary lymphedema ultrasound mapping and characterization. Int Angiol. 2019 Aug;38(4):334-342.
  37. 037Crippa A, Menegatti E, Zini F, Tessari L, Taibi A, Maietti E, Gianesini S. Safety and short-term efficacy of telangiectasia treatment by means of an innovative combination of 532 and 808 nm transdermal diode laser. Phlebology. 2019 Apr 6.
  38. 038Gianesini S, Mosti G, Sibilla MG, Diaz J, Raffetto J, Maietti E, Zamboni P, Menegatti E. Lower limb volume in healthy subjects following walking with compression stockings. J Vasc Surg Venous Lymphat Disord 2019, in press.
  39. 039Mini-invasive foam sclerotherapy assisted ligation vs surgical flush ligation for incompetent sapheno-popliteal junction treatment. Phlebology 2019, in press.
  40. 040Gianesini S, et al. Lower limbs venous kinetics and consequent impact on drainage direction. Phlebology 2018, in press.
  41. 041Gianesini S, et al. Comparison between duplex ultrasound and multigate quality Doppler profile software in the assessment of lower limb perforating vein direction. Eur J Vasc Endovasc Surg 2018, in press.
  42. 042Healthy subjects lower limb volume & perceived exertion following a standardized walk with and without graduated compression. J Vasc Surg 2018, in press.
  43. 043Ultrasound monitoring of the jugular venous pulse during space missions: a proof of concept. Ultrasound Med Biol 2017, in press.
  44. 044Gianesini S. CHIVA: theory, practice and outcomes. Vein 2017;7.
  45. 045Spath P, Tisato V, Gianesini S, Tessari M, Menegatti E, Manfredini R, Occhionorelli S, Secchiero P, Zamboni P. The calendar of cytokines: seasonal variation of circulating cytokines in chronic venous insufficiency. JRSM Cardiovasc Dis 2017, in press.
  46. 046High resolution M-mode evaluation of jugular vein valves in patients with neurological and neurosensory disorders. Curr Neurovasc Res 2017, in press.
  47. 047Cappelli M, Molino-Lova R, Giangrandi I, Ermini S, Gianesini S. Ligation of the sapheno-femoral junction tributaries as risk factor for groin recurrence. J Vasc Surg Venous Lymphat Disord 2017, in press.
  48. 048Gianesini S. Expert opinion on hot topics in phlebology. Endovascular Today 2017;16:51.
  49. 049Gianesini S, et al. Femoral vein valve incompetence as a risk factor for junctional recurrence. Phlebology 2016, in press.
  50. 050Gianesini S, Tessari M, Bacciglieri P, Malagoni AM, Menegatti E, Occhionorelli S, Basaglia N, Zamboni P. A specifically designed aquatic exercise protocol to reduce chronic lower limb edema. Phlebology 2016, in press.
  51. 051Zamboni P, Spath P, Tisato V, Tessari M, Dalla Caneva P, Menegatti E, Occhionorelli S, Gianesini S, Secchiero P. Oscillatory flow suppression improves inflammation in chronic venous disease. J Surg Res. 2016 Sep;205(1):238-45.
  52. 052Zamboni P, Menegatti E, Cittanti C, Sisini F, Gianesini S, Mascoli F, Salvi F. Fixing the jugular flow reduces ventricles volume and improves brain perfusion. J Vasc Surg Venous Lymphat Disord 2016, in press.
  53. 053Sisini F, Tessari M, Menegatti E, Vannini ME, Gianesini S, Tavoni V, Gadda G, Gambaccini M, Taibi A, Zamboni P. Clinical applicability of assessment of jugular flow over the individual cardiac cycle compared with current ultrasound methodology. Ultrasound Med Biol 2016, in press.
  54. 054Tessari L, Gianesini S. Foam sclerotherapy safety: news from the lab. Flebologia 2016;42(1):41-43.
  55. 055Gianesini S, Menegatti E, Malagoni AM, Occhionorelli S, Zamboni P. Mini-invasive high-tie by clip apposition versus crossectomy by ligature: long-term outcomes and review of the available therapeutic options. Phlebology 2016, in press.
  56. 056Zollino I, Zuolo M, Gianesini S, Pedriali M, Sibilla AG, Tessari M, Carinci F, Occhionorelli S, Zamboni P. Autologous adipose-derived stem cells: basic science, technique, and rationale for application in ulcer and wound healing. Phlebology 2016, in press.
  57. 057Zamboni P, Gianesini S. Surgical technique for deep venous reflux suppression in femoral vein duplication. Eur J Vasc Endovasc Surg 2016, in press.
  58. 058Franceschi C, Cappelli M, Gianesini S, Mendoza E, Ermini S, Passariello F, Zamboni P. Venous hemodynamic changes in lower limb venous disease: the UIP consensus according to scientific evidence. Int Angiol. 2016 Jun;35(3):236-352.
  59. 059Gianesini S, Tessari M, Menegatti E, Spath P, Vannini ME, Occhionorelli S, Zamboni P. Comparison among 18 mmHg and 23 mmHg elastic stockings effect on leg volume and tiredness after golf. Int Angiol 2016, in press.
  60. 060Gianesini S, Antignani PL, Tessari L. Pelvic congestion syndrome: does one name fit all? Phlebolymphology, in press.
  61. 061Borghi A, Gianesini S, Pedriali M, Stefanelli A, Mangiola G, Dalla Caneva P, Lanza G, Virgili AR, Zamboni P. An apparently untreatable ulcer of the face. Int Wound J. 2016 Jan 10.
  62. 062Gianesini S, Gafà R, Occhionorelli S, Menegatti E, Malagoni AM, Spath P, Zamboni P. Histologic and sonographic features of holmium laser in chronic venous disease treatment. Int Angiol, in press.
  63. 063Gianesini S, Menegatti E, Zuolo M, Tessari M, Spath P, Ascanelli S, Occhionorelli S, Zamboni P. Laser-assisted strategy for reflux abolition in a modified CHIVA approach. Veins & Lymphatics 2015.
  64. 064Gianesini S, Cavezzi A, Mosti G, Tessari L, Zini F, Urso S, Campana F, Tessari M, Della Caneva P, Espinoza F, Rocha R, Neuhardt D, Mowatt-Larssen E, Zygmunt J, Cortesi S, Morrison T, Morrison N. A phlebo-lymphology humanitarian trip to Matagalpa, Nicaragua. Veins & Lymphatics.
  65. 065Tisato V, Zauli G, Gianesini S, Menegatti E, Brunelli L, Manfredini R, Zamboni P, Secchiero P. Modulation of circulating cytokine-chemokine profile in patients affected by chronic venous insufficiency undergoing surgical haemodynamic correction. J Immunol Res 2014;2014:473765.
  66. 066Zamboni P, Mascoli F, Salvi F, Menegatti E, Gianesini S, Tisato V, Secchiero P. Ultrastructure of internal jugular vein defective valves. Phlebology 2014 Jun 27.
  67. 067Gianesini S, Occhionorelli S, Menegatti E, Zuolo M, Tessari M, Spath P, Ascanelli S, Zamboni P. CHIVA strategy in chronic venous disease treatment: instructions for users. Phlebology 2014 Apr 22.
  68. 068Menegatti E, Tessari M, Gianesini S, Vannini ME, Sisini F, Zamboni P. Human internal jugular valve M-mode ultrasound characterization. Curr Neurovasc Res 2014.
  69. 069Tisato V, Zauli G, Rimondi E, Gianesini S, Brunelli L, Menegatti E, Zamboni P, Secchiero P. Inhibitory effect of natural anti-inflammatory compounds on cytokines released by chronic venous disease patient-derived endothelial cells. Mediators Inflamm 2013;2013:423407.
  70. 070Gianesini S, Tisato V, Menegatti E, Volpi I, Voltan R, Occhionorelli S, Secchiero P, Zamboni P. Oscillatory turbulent flow in chronic venous disease induces pro-inflammatory and reparative biological signaling. J Vasc Surg Venous Lymphat Disord 2013;1:108.
  71. 071Tisato V, Secchiero P, Rimondi E, Gianesini S, Menegatti E, Casciano F, Zamboni P, Zauli G. GM-CSF exhibits anti-inflammatory activity on endothelial cells derived from chronic venous disease patients. Mediators Inflamm 2013;2013:561689.
  72. 072Gianesini S, Menegatti E, Zuolo M, Tessari M, Ascanelli S, Occhionorelli S, Zamboni P. Feasibility of endovenous laser in type I CHIVA procedure: a new minimally invasive and saphenous sparing therapeutic option. Veins & Lymphatics, in press.
  73. 073Tisato V, Zamboni P, Menegatti E, Gianesini S, Volpi I, Zauli G, Secchiero P. Endothelial PDGF-BB produced ex vivo correlates with relevant hemodynamic parameters in patients affected by chronic venous disease. Cytokine. 2013 Aug;63(2):92-6.
  74. 074Gianesini S, Menegatti E, Mascoli F, Salvi F, Bastianello S, Zamboni P. The omohyoid muscle entrapment of the internal jugular vein: a still unclear pathogenetic mechanism. Phlebology. 2013 May 16.
  75. 075Tisato V, Zauli G, Voltan R, Gianesini S, di Iasio MG, Volpi I, Fiorentini G, Zamboni P, Secchiero P. Endothelial cells obtained from patients affected by chronic venous disease exhibit a pro-inflammatory phenotype. PLoS One 2012;7(6):e39543.
  76. 076Gentili V, Gianesini S, Balboni PG, Menegatti E, Rotola A, Zuolo M, Caselli E, Zamboni P, Di Luca D. Panbacterial real-time PCR to evaluate bacterial burden in chronic wounds treated with Cutimed Sorbact. Eur J Clin Microbiol Infect Dis. 2012 Jul;31(7):1523-9.
  77. 077Franceschi C, Gianesini S, Bahnini A, Laurian C, Menegatti E, Zamboni P. The recurrent cervical swelling syndrome. Phlebology. 2012 Mar;27(2):90-2.
  78. 078Zamboni P, Gianesini S, Menegatti E, Tacconi G, Palazzo A, Liboni A. Great saphenous varicose vein surgery without sapheno-femoral junction disconnection. Br J Surg. 2010 Jun;97(6):820-5.
  79. 079Zamboni P, Galeotti R, Menegatti E, Malagoni AM, Gianesini S, Bartolomei I, Mascoli F, Salvi F. A prospective open-label study of endovascular treatment of chronic cerebrospinal venous insufficiency. J Vasc Surg. 2009 Dec;50(6):1348-58.
  80. 080Zamboni P, Consorti G, Galeotti R, Gianesini S, Menegatti E, Tacconi G, Carinci F. Venous collateral circulation of the extracranial cerebrospinal outflow routes. Curr Neurovasc Res. 2009 Aug;6(3):204-12.
  81. 081Gianesini S, Menegatti E, Tacconi G, Scognamillo F, Liboni A, Zamboni P. Echo-guided foam sclerotherapy treatment of venous malformation involving the sciatic nerve. Phlebology. 2009;24(1):46-7.
  82. 082Gemmati D, Tognazzo S, Catozzi L, Carandina S, De Palma M, Tacconi G, Gianesini S, Scapoli GL, Zamboni P. Influence of genetic polymorphism in ulcer healing process after superficial venous surgery. J Vasc Surg. 2006 Sep;44(3):554-62.
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